Cyclization of Isothiosemicarbazones. III. Formation of Thiazolines and Thiazoles through Potential Sulfonium Salts from N,S-Disubstituted Isothiosemicarbazones

Article abstract of DOI:10.1246/bcsj.53.3289

The reaction 3,4-disubstituted isothiosemicarbazones with α-bromo ketones led to the formation of 4-thiazoline derivatives, the substituents on the sulfur atom being cleaved as bromides.They are identical with the compounds obtained by the condensation of