Synthesis and biological investigation of S-aryl-S-DABO derivatives as HIV-1 inhibitors

Article abstract of DOI:10.1016/j.bmcl.2006.03.080

S-Aryl-S-DABO derivatives, a novel subclass of S-DABO anti-HIV-1 agents, were synthesized via Ullmann type reaction starting from the corresponding 2-thiouracils by the aid of microwave irradiation. The results of their evaluation as inhibitors of RT are