Journal of the Chemical Society. Chemical communications p. 1191 - 1193 (1980)
Update date:2022-08-05
Topics:
Divakar, K. J.
Reese, Colin B.
In alkaline solution, 8-carboxamido-2'-O-tosyladenosine (4e; R2 = R3 = H), which may be prepared from adenosine in 7 steps, readily cyclizes to give (5); in neutral or weakly basic solution, it undergoes virtually quantitative conversion into ara-A (1a).
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Doi:10.1016/0040-4039(80)80207-3
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