
Tetrahedron Letters p. 3885 - 3888 (1980)
Update date:2022-08-05
Topics:
Takahashi, Takashi
Ikeda, Hiroshi
Tsuji, Jiro
Palladium -catalyzed carbonylation of 3,5-dimethoxybenzyl chloride (13) with benzyl 7-hydroxyoctanoate (12) afforded benzyl 7-(3,5-dimethoxyphenylacetoxy)octanoate (6) in 70percent yield, which is the precursor of Curvularin (4).The ester (12) was easily prepared from the butadiene telomer obtained by the palladium-catalyzed reaction of butadiene with acetic acid.
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