Journal of Organic Chemistry p. 2213 - 2215 (1981)
Update date:2022-08-05
Topics:
Francis, Robert F.
Howell, Howard M.
Fetzer, Donald T.
A series of 2,5-dialkyl(phenyl)-2,5-dihydropyridines (2) was prepared by reacting 1-lithio-2-alkyl(phenyl)-1,2-dihydropyridines (1) with alkyl halides.The 2,5-dihydropyridines (2) are stable when maintained cold under a nitrogen atmosphere, and these compounds react with alkyl(phenyl)lithium compounds by nucleophilic addition to the C=N moiety.The resultant products are 2,3,6-trialkyl(phenyl)-1,2,3,6-tetrahydropyridines (4) which can be oxidized (selenium) to the corresponding 2,3,6-trialkylpyridines (5).
View Morewebsite:http://www.u-chemo.com
Contact:+86-21-61558312
Address:Dong Fang Road,
Shanghai Sungo Technology Chemical Co., Ltd
Contact:0086-21-51385579
Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
Taizhou Crene Biotechnology co.ltd
Contact:86-576-88813233 88205808
Address:Economic Developed Zone of Taizhou Zhejiang China
Shanghai Zhihua ChemTech Co., Ltd.
Contact:+86-13774313779
Address:Room 817 Suite B 3333 Shenjiang Road
Hangzhou Yanshan Chemical Co.,Ltd.
Contact:86-571- 87698076
Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
Doi:10.1016/S0040-4020(01)89379-0
(1994)Doi:10.1021/ja9726668
(1998)Doi:10.1021/ol802141g
(2008)Doi:10.1039/c6ra28654b
(2017)Doi:10.1021/jo01231a010
(1936)Doi:10.1007/BF00899326
(1950)