JANUS WEDGES: A new approach towards nucleobase-pair recognition

DOI: 10.1039/cc9960002443

Source and publish data:

Chemical Communications p. 2443 - 2444 (1996)

Update date:2022-07-30

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Authors:

Branda, Neil

Kurz, Guido

Lehn, Jean-Marie

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Article abstract of DOI:10.1039/cc9960002443

The two-faced JANUS-type heterocycles 1a and 1b are designed to recognize a cytosine-uracil mismatched base-pair by insertion in a wedge-like fashion between the bases to give a triad motif utilizing the maximum number of Watson-Crick interactions, as sho

Full text of DOI:10.1039/cc9960002443

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