European Journal of Organic Chemistry p. 4624 - 4627 (2015)
Update date:2022-08-04
Topics:
Halli, Juliette
Hofman, Kamil
Beisel, Tamara
Manolikakes, Georg
A general synthesis of N-acyl-N,O-acetals from aldehydes, amides and alcohols is reported. This new method consists of two single steps: (a) magnesium-mediated addition of an amide or carbamate to an aldehyde and (b) acid-catalyzed conversion of the N-acylhemiaminal to the N-acyl-N,O-acetal. This two-step protocol allows the multigram synthesis of various N-acyl-O-alkyl-N,O-acetals.
View MoreContact:18698110882
Address:1303 No2 building,LuoMa Garden,YongAn Road,Hexi District,Tianjin city
Jiangsu Haian Petro chemical Plant
Contact:+86-513-88902723
Address:99, Changjiang West Road, Haian County, Jiangsu
Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.
Contact:+86-(574)-81110986
Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo
Meryer (Shanghai) Chemical Technology Co., Ltd.
website:http://www.meryer.com/cn/index/
Contact:+86-755-86170518
Address:Minhang,Shanghai, China
Zhejiang Chemicals Import & Export Corporation
Contact:86-571-87043088
Address:No.37,Qingchun Road,Hangzhou,China
Doi:10.1016/S1381-1169(99)00143-0
(1999)Doi:10.1021/jf101974y
(2010)Doi:10.1039/c8sc02126k
(2018)Doi:10.1002/ejic.200300751
(2004)Doi:10.1021/jm00332a015
(1964)Doi:10.1021/ol050730h
(2005)
