
Journal of the Chemical Society. Perkin transactions I p. 344 - 348 (1981)
Update date:2022-08-03
Topics:
Jones, Winton D.
The aminolysis of 4-<(4-oxo-4H-1-benzopyran-3-yl)methylene>-2-phenyl-1,3-oxazol-5(4H)-one with diethylamine gave N-<1-(diethylamino)-1-oxo-3-(4-oxo-4H-1-benzopyran-3-yl)prop-2-en-2-yl>benzamide.The hydrolysis of 2-methyl-4-<(4-oxo-4H-1-benzopyran-3-yl)methylene>-1,3-oxazol-5(4H)-one gave the α-keto-acid, which could be converted into amino-acid derivatives.Condensation of 2-methylchromone with diethyl oxalate, 2-formyl-NN-diethylbenzamide, and 2-formylbenzoic acid gave the α-keto-acid, (E)-NN-diethyl-2-<2-(4-oxo-4H-1-benzopyran-2-yl)vinyl>benzamide, and (E)-2-<(4-oxo-4H-1-benzopyran-2-yl)vinyl>benzoic acid, respectively.
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(1981)