Journal of Organic Chemistry p. 2675 - 2679 (1983)
Update date:2022-08-02
Topics: Intramolecular Ring Closure
McClure, D. E.
Lumma, P. K.
Arison, B. H.
Jones, J. H.
Baldwin, J. J.
The synthesis of the tetrahydroindeno<1,2-b>-1,4-oxazin-3(2H)-one system from phenylalanine is described.Conversion of the intermediate vicinal amino alcohol to the 1,4-oxazine was accomplished via BF3*Et2O-catalyzed ring closure of a β-hydroxydiazoacetam
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