REGIOSPECIFIC ALLYLATION OF SULFUR SUBSTITUTED ACTIVE METHYLENE COMPOUNDS WITH ALLYLIC BROMIDES

DOI: 10.1246/cl.1980.1365

Source and publish data:

Chemistry Letters p. 1365 - 1368 (1980)

Update date:2022-08-02

Topics:

Authors:

Ono, Noboru

Miyake, Hideyoshi

Tanabe, Yo

Tanaka, Kazuhiko

Kaji, Aritsune

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1980.1365

Allylation of sulfur substituted active methylene compounds such as RSCH2Y with allylic bromides in the presence of bases gives a mixture of the S_N2-product and the apparent S_N2'-product.The former product is selectively obtained in alkylation in a nonpolar solvent.Synthetic utility of this regiospecific allylation is demonstrated in the simple synthesis of pellitorine.

Full text of DOI:10.1246/cl.1980.1365

Products guided by the article

Product name:(E)-2-Phenylsulfanyl-hex-4-enoic acid tert-butyl ester

Cas No:77486-60-3

R&D Labs maybe for 77486-60-3

Shanxi Sanwei Group Co.,Ltd

Contact:0086-357-6662688

Address:Zhaocheng town, Hongtong County, Linfen City, Shanxi Province
HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Beijing Wisdom Chemicals Co., Ltd.

Contact:+86-10-52350335

Address:F2, BLDG 19, Liando Valley U, Majuqiao, Tongzhou District, Beijing, China
Zhushan County Tianxin Pharmaceutical & Chemical Co., Ltd.

Contact:0086-719-4224892

Address:Tutang Road, Chengguan Town, Zhushan County, Hubei Province
Shanghai Forever Biotech Co., Ltd.

Contact:+86-21-69734790

Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.

Relevant to this article

Structural and spectral studies of N-(3-hydroxypyridine-2-yl)-5- hydroxysalicylideneimine and its dimethyltin(IV) complex

Doi:10.1016/j.molstruc.2004.06.023
(2004)
Preparation and evaluation of bipyridyl-tagged reagents and scavengers

Doi:10.1016/j.tet.2004.05.106
(2004)
A facile conversion of 2-substituted acrylamides to 1,3-disubstituted 3-bromo-2-azetidinones

Doi:10.1080/00397919308009807
(1993)
Synthesis and structure-activity relationship of (lactamylvinyl)cephalosporins exhibiting activity against staphylococci, pneumococci, and enterococci

Doi:10.1021/jm950886v
(1996)
SYNTHESIS OF POLYSACCHARIDES. 12. SYNTHESIS OF REGULAR GLUCORHAMNAN -->(-->6-D-Glcp 1 β/--> 4Rhap 1 α/-->)-->/n

Doi:10.1007/BF00962279
(1981)
On the structure of the 'iminourazoles'

Doi:10.1002/ardp.19813140616
(1981)

Article Doi