Synthesis and Antimicrobial Evaluation of Some Novel Pyrido[2,3-d] Pyrimidine Derivatives and Their Ribofuranosides

Article abstract of DOI:10.1002/jhet.3203

2-Amino-3-cyano-4,6-disubstituted pyridines 2a–c on treatment with arylisocyanate and arylisothiocyanate afforded 4-imino-3,5,7-trisubstituted pyrido[2,3-d] pyrimidin-2(1H)-ones 3a–c and 4-imino-3,5,7-trisubstituted pyrido[2,3-d]pyrimidin-2(1H)-thiones 4a