STEREOSPECIFIC TRANSFORMATION OF D-SUGAR TO L-SUGAR IN COMPLEX AMINOGLYCOSIDE. SYNTHESIS OF A KANAMYCIN B ANALOG HAVING 2,6-DIAMINO-2,4,6-TRIDEOXY-L-ARABINO-HEXOPYRANOSE

Article abstract of DOI:10.1016/0040-4039(81)80045-7

A 4'-ene derivative of kanamycin B (4) was derived from the epoxide (1) by oxidative elimination of the 4'-phenylseleno group into the allylic alcohol (3).The title compound, O-(2,6-diamino-2,4,6-trideoxy-β-L-arabino-hexopyranosyl)-(1<*>4)-O-<3-amino-3-de