SYNTHESIS OF OLIVANIC ACID ANALOGUES: A FACILE ROUTE TO 3-(2-PYRIMIDINYLTHIO-)SUBSTITUTED DERIVATIVES

Article abstract of DOI:10.1016/S0040-4039(00)71137-3

3-(3-Pyrimidinylthio-)substituted olivanic acid analogues, with and without a C-6 hydroxyethyl substituent, have been synthetized in high yield using an intramolecular Wittig reaction followed by deprotection to afford zwitterions with high antibacterial