Synthesis and Hypoglycemic Activity of Phenylalkyloxiranecarboxylic Acid Derivatives

DOI: 10.1021/jm00344a003

Source and publish data:

Journal of Medicinal Chemistry p. 109 - 113 (1982)

Update date:2022-09-26

Topics:

Authors:

Eistetter, Klaus

Wolf, Horst P. O.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00344a003

A series of new 2-(phenylalkyl)oxirane-2-carboxylic acids has been synthesized and studied for its effects on the concentration of blood glucose.Most of the compounds exhibit remarkable blood glucose lowering activities in fasted rats.Structure-activity s

Full text of DOI:10.1021/jm00344a003

Products guided by the article

Product name:5-(4-methylphenyl)-2-methylenevaleric acid ethyl ester

Cas No:78573-46-3

R&D Labs maybe for 78573-46-3

Shandong Wanda Organosilicon New Material Co., Ltd

Contact:+86-21-54177116;54302881

Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
Hubei Sibo Technology Co.,Ltd.

Contact:0715-6597222

Address:Pan Jia Wan fan Lake Chemical Industrial Park ,Xianning City, Hubei, China
LINYI FUDE FINE CHEMICAL CO.,LTD

Contact:86-539-2361184

Address:YISHUI, LINYI,SAHNDONG,CHINA
Anhui Sholon New Material Technology Co., Ltd.

website:http://www.sholonchem.com

Contact:+86-550-5261666

Address:4/F Block B, Beijing Chemical Building.No.520 Tianrun Road ,Science & Education Town Wujin District, Changzhou City Jiangsu Province
Neworld Chemical Co., Ltd Shanghai(expird)

Contact:+86-21-62202658

Address:11F, Blvd 2, No. 1969 PuXing Rd, Shanghai

Relevant to this article

Synthesis of new pyrrolo[3,2-l]acridinones and pyrrolo[3,2-c][1,8]naphthyridinones by condensation of methoxybenzenes or phenols with isobutyric aldehyde and o-aminonitriles

Doi:10.1007/s10593-018-2195-0
(2017)
Determining Essential Requirements for Fluorophore Selection in Various Fluorescence Applications Taking Advantage of Diverse Structure-Fluorescence Information of Chromone Derivatives

Doi:10.1021/acs.jmedchem.0c01508
(2021)
Fluorous phase-switching of pyridyl-tagged substrates/products

Doi:10.1021/ol048994b
(2004)
Cyclopeptide Alkaloids. Synthetic, Spectroscopic and Conformational Studies of Phencyclopeptine Model Compounds

Doi:10.1021/jo01312a001
(1980)
A Serendipitous Synthesis of Bis-Heterocyclic Spiro 3(2 H)-Furanones

Doi:10.1021/acs.joc.5b02350
(2016)
Oxidations with Cerium(IV) Sulfate: Intramolecular Cyclization of N-Benzyl-&β-aminoketones Yielding 4-Benzoyl-1,2,3,4-tetrahydroisoquinolines

Doi:10.1002/ardp.19873200715
(1987)

Article Doi