Purines. xxxviii. A general synthesis of 7,9-dialkyladeninium salts from 9-alkyladenines by regioselective alkylation: Utilization of an N6-alkoxy group as a control synthon

Article abstract of DOI:10.1248/cpb.38.652

A detailed account is given of the general synthetic route to 7,9-dialkyladeninium salts (16 18) from N⁶-alkoxy-9-alkyladenines (type 5 or 11--13), readily obtainable from 9-alkyladenines in three steps involving N(1)-oxidation, O-alkylation, a