Helvetica Chimica Acta p. 425 - 429 (1981)
Update date:2022-08-04
Topics:
Tronchet, Jean M. J.
Tronchet, Jeannine F.
Starting from 5-O-benzoyl-3-C-methylidene-3-deoxy-1,2-O-isopropylidene-α-D-erythro-pentofuranose (11) the title compound 8 has been prepared.Its α-anomer (9) and the acyclic sugar nucleoside 10 have been obtained as by-products.Adenosine deaminase slowly deaminated 8, 9 being not affected.Compound 8 exhibited no antiviral activity, whereas one of its saturated analogues (13) inhibited the multiplication of the herpes-1 (HF) virus.
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