A CONVENIENT METHOD FOR THE DIRECT PREPARATION OF KETONES FROM 2-(6-(2-METHOXYETHYL)PYRIDYL) CARBOXYLATES AND ALKYL IODIDES BY USE OF ZINC DUST AND A CATALYTIC AMOUNT OF NICKEL DICHLORIDE

DOI: 10.1246/cl.1981.531

Source and publish data:

Chemistry Letters p. 531 - 534 (1981)

Update date:2022-07-30

Topics:

Authors:

Onaka, Makoto

Matsuoka, Yoshio

Mukaiyama, Teruaki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1981.531

Treatment of 2-(6-(2-methoxyethyl)pyridyl) carboxylates with alkyl iodides in the presence of zinc dust and a catalytic amount of NiCl2 in DMF at 50 deg C affords unsymmetrical ketones in good yields by a one-pot procedure.

Full text of DOI:10.1246/cl.1981.531

Products guided by the article

Product name:4-Phenyl-butyric acid [2,2']bipyridinyl-6-yl ester

Cas No:78428-02-1

R&D Labs maybe for 78428-02-1

Xiamen Sinchem Imp.&Exp. Co.,Ltd.

website:http://www.sinchemind.com

Contact:86-592-2237696

Address::No.500, Xinlong Rd, Xiamen, China
Xi'an Harmonious Natural Bio-Technology Co., Ltd.

website:http://www.xahnb.com

Contact:+86-18092068319

Address:huilinhuacheng 10-2104
Goldwills Pharmaceuticals Co., Ltd.

Contact:0916-2237889 13991621155

Address:North Suburb of Hanzhong city, Shaanxi Province
EnBridge PharmTech Co., Ltd.

website:http://www.enbridgepharm.com

Contact:+86-510-83591909

Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China
WUXI HONOR SHINE CHEMICAL CO.,LTD

Contact:+86-510-83593312

Address:No.1699 Huishan avenue,Huishan district,Wuxi ,Jiangsu,China,214177.(Wuxi Huishan Ecomonic Develop Zone )

Relevant to this article

Thiol compounds. II. Synthesis and antihypertensive activity of mercaptoacylamino acids

Doi:10.1248/cpb.29.940
(1981)
A quantitative study of substituent effects on oxidative cyclization of some 2-methylsubstituted aldehydes. Thiosemicarbazones induced by ferric chloride

Doi:10.1002/jhet.5570330353
(1996)
Synthesis of reactive intermediates for natural cyclopentane derivatives from (-)-quinic acid: Preparation of 11α-hydroxy-13-oxaprostanoic acid

Doi:10.1002/hlca.19810640419
(1981)
Doi:10.1021/ja01611a045
(1955)
Stereoselective oxidation of aryl-substituted vicinal diols into chiral α-hydroxy aldehydes by re-engineered propanediol oxidoreductase

Doi:10.1021/cs400824h
(2013)
Stereoselective reductive rearrangement of α-hydroxy epoxides: A new method for synthesis of 1,3-diols

Doi:10.1021/jo981097z
(1999)

Article Doi