A CONVENIENT METHOD FOR THE DIRECT PREPARATION OF KETONES FROM 2-(6-(2-METHOXYETHYL)PYRIDYL) CARBOXYLATES AND ALKYL IODIDES BY USE OF ZINC DUST AND A CATALYTIC AMOUNT OF NICKEL DICHLORIDE

DOI: 10.1246/cl.1981.531

Source and publish data:

Chemistry Letters p. 531 - 534 (1981)

Update date:2022-07-30

Topics:

Authors:

Onaka, Makoto

Matsuoka, Yoshio

Mukaiyama, Teruaki

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Article abstract of DOI:10.1246/cl.1981.531

Treatment of 2-(6-(2-methoxyethyl)pyridyl) carboxylates with alkyl iodides in the presence of zinc dust and a catalytic amount of NiCl2 in DMF at 50 deg C affords unsymmetrical ketones in good yields by a one-pot procedure.

Full text of DOI:10.1246/cl.1981.531

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