SYNTHETIC STUDIES TOWARD MAYTANSINOIDS. PREPARATION OF THE OPTICALLY ACTIVE INTERMEDIATES FROM D-MANNOSE

DOI: 10.1246/cl.1981.457

Source and publish data:

Chemistry Letters p. 457 - 460 (1981)

Update date:2022-09-26

Topics: Synthetic studies Intermediates Optically active D-mannose Maytansinoids

Authors:

Isobe, Minoru

Ichikawa, Yoshiyasu

Kitamura, Masato

Goto, Toshio

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Article abstract of DOI:10.1246/cl.1981.457

Optically active intermediates (15 and 23) for maytansine were synthesized from D-mannose via heteroconjugate addition of methyllithium as a crucial step.

Full text of DOI:10.1246/cl.1981.457

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