The Penems, a New Class of β-Lactam Antibiotics. 5. Total Synthesis of Racemic 6-α-Hydroxyethylpenemcarboxylic Acids

DOI: 10.1021/ja00526a045

Source and publish data:

Journal of the American Chemical Society p. 2039 - 2043 (1980)

Update date:2022-07-30

Topics: Total synthesis Racemic Penems

Authors:

Pfaendler, H. R.

Gosteli, J.

Woodward R. B.

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Article abstract of DOI:10.1021/ja00526a045

The novel racemic threo-trans-6-α-hydroxyethylpenem-3-carboxylic acid 3t and its erythro-trans isomer 3e have been prepared over 13 steps from acetoxyazetidinone 4.

Full text of DOI:10.1021/ja00526a045

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