Synthesis and biological activities of a new set of irreversibly acting 2- (4'-isothiocyanatobenzyl)imidazoline analogs in rat thoracic aorta

DOI: 10.1021/jm00038a017

Source and publish data:

Journal of Medicinal Chemistry p. 1874 - 1881 (1994)

Update date:2022-07-30

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Authors:

Slavica Slavica

Lei Lei

Patil Patil

Kerezy Kerezy

Feller Feller

Miller Miller

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Article abstract of DOI:10.1021/jm00038a017

IBI [2-(4'-isothiocyanatobenzyl)imidazoline, 3] has been shown to cause slow-onset, long-lasting contractions of rat thoracic aorta through a non- α-adrenergic receptor (non-α-AR) mediated mechanism. A series of IBI- related analogs 7-14 and 16 was prepar

Full text of DOI:10.1021/jm00038a017

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