
Tetrahedron Letters p. 1587 - 1590 (1981)
Update date:2022-08-05
Topics: Retrosynthetic analysis Purification and characterization Scale-up Stereochemistry Control Biological Evaluation Ring Formation Functional Group Transformations
Corey, E. J.
Marfat, Anthony
Hoover, Dennis J.
Non enzyamatic hydration of leukotriene A (1), the biogenetic precursor of leukotriene B (2) affords among other products two diastereomeric 6-trans-isomers of 2, the first stereospecific and efficient syntheses of which are recorded herein.
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