Angewandte Chemie - International Edition p. 4324 - 4327 (2004)
Update date:2022-09-26
Topics:
Shi, Bingfeng
Wu, Hao
Yu, Biao
Wu, Jiarui
An aldol condensation is the key to the eight-step linear synthesis of 23-oxa analogues of OSW-1 (e.g. 2) in more than 20% overall yield from the industrially produced steroid 1. Compound 2 is up to 2000 times more potent than cisplatin as an inhibitor of
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