Helvetica Chimica Acta p. 560 - 579 (1986)
Update date:2022-08-04
Topics:
Koller, Manuel
Karpf, Martin
Dreiding, Andre S.
The gas-flow thermolysis of 1-isobutenyl alkynyl or 2-methyphenyl alkynyl ketones were found to lead to phenols and cyclopentenones or to naphthols and indanones, respectively.These conversions involve two cyclization processes so far unknown with α-alkynones; they are interpreted as intramolecular additions of an allylic or a benzylic C,H bond to a triple bond which may occur in two directions.In addition, the cyclopentenones formed by the α-alkynone cyclization, a known carbene process yielding 5-rings, were also found.The available evidence ruled out a carbene process yielding 6-rings.The addition process yielding 5-rings was applied to a short (but low yield) synthesis of methylenomycin B.
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Doi:10.1039/P19810002398
(1981)Doi:10.1016/S0040-4039(00)84936-9
(1986)Doi:10.1016/0008-6215(90)84116-C
(1990)Doi:10.1016/j.ejmech.2019.111764
(2019)Doi:10.1021/ja01163a094
(1950)Doi:10.1002/chem.201003105
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