Michael Addition to trans-Enediones: A Facile Route to 2,3,4,5-Tetrasubstituted Furans

DOI: 10.1039/P19810002398

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2398 - 2400 (1981)

Update date:2022-08-04

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Authors:

Antonioletti, Roberto

D'Auria, Maurizio

Piancatelli, Giovanni

Scettri, Arrigo

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Article abstract of DOI:10.1039/P19810002398

The enediones (2) are useful starting materials for a two-step synthesis of tetrasubstituted furans, which are not otherwise easily available.Michael addition of active methylene compounds to the enediones (2) led to the two regioisomeric adducts (8) and (9), which then cyclized to furans under very mild conditions

Full text of DOI:10.1039/P19810002398

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