RSC Medicinal Chemistry p. 665 - 675 (2020)
Update date:2022-08-05
Topics: Structural features Specificity
Bernasconi, Elena
Bertoni, Francesco
Caflisch, Amedeo
Cascione, Luciano
Dong, Jing
Gaudio, Eugenio
Jessen-Trefzer, Claudia
Nevado, Cristina
Pachmayr, Johanna
Sartori, Giulio
Spiliotopoulos, Dimitrios
Tarantelli, Chiara
Unzue, Andrea
Zahler, Stefan
Zhao, Hongtao
?led?, Pawe?
The X-ray structure of the catalytic domain of the EphA3 tyrosine kinase in complex with a previously reported type II inhibitor was used to design two novel quinoxaline derivatives, inspired by kinase inhibitors that have reached clinical development. Th
View Morewebsite:http://www.tbbmed.com
Contact:86--21-50498136
Address:Room 6002, Building 7-1, No.160 Basheng Road,Pudong Area,Shanghai China
Contact:+86-158-05817090
Address:ROOM 9F, FLAT 2, GUODU DEVELOPING BLDG, No.182, ZHAOHUI ROAD
Huludao Tianqi Shengye Chemical Co.,Ltd.
Contact:0086 429 2075777
Address:Area B,Shipbuilding Industry Park,Beigang District,Huludao City,Liaoning prov.,China
Contact:18669908765
Address:Zibo City, Shandong Province, P.R.China
Contact:+86-25-83719363
Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China
Doi:10.1055/s-1981-29579
(1981)Doi:10.1002/anie.201501257
(2015)Doi:10.1246/cl.1981.1283
(1981)Doi:10.1002/anie.201406393
(2014)Doi:10.1016/S0040-4020(01)92358-0
(1981)Doi:10.1016/S0040-4020(01)92352-X
(1981)