Synthesis of new 2′,3′-dideoxy-6′,6′-difluoro- 3′-thionucleoside from gem-difluorohomoallyl alcohol

DOI: 10.1021/ol048423j

Source and publish data:

Organic Letters p. 3941 - 3944 (2004)

Update date:2022-08-05

Topics:

Authors:

Wu, Yun-Yun

Zhang, Xingang

Meng, Wei-Dong

Qing, Feng-Ling

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Article abstract of DOI:10.1021/ol048423j

(Chemical Equation Presented) 2′,3′-Dideoxy-6′,6′- difluoro-3′-thionucleoside 1b, an analogue of 3Tc that has high biological activities against HIV and HBV, has been synthesized from gem-difluorohomoallyl alcohol 3 in an efficient way. The key intermedia

Full text of DOI:10.1021/ol048423j

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