Influence of N(2)-substitution in the alkylation of (4S)-alkyl-2,4-dihydro- 1H-pyrazino[2,1-b]quinazoline-3,6-diones

DOI: 10.1016/j.tetasy.2004.07.034

Source and publish data:

Tetrahedron Asymmetry p. 3045 - 3058 (2004)

Update date:2022-08-03

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Authors:

Hernandez, Fernando

Morales, Viviana

Buenadicha, Felix L.

Soellhuber, Monica

Avendano, Carmen

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Article abstract of DOI:10.1016/j.tetasy.2004.07.034

1-Alkylation of O(3)-lactim, N(11)-azaenolate dilithium species derived from N(2)-H compounds 1a and 1b and the lithium azaenolates derived from the N(2)-phenyl and N(2)-(1-arylethyl) substituted compounds 2, 3 and 4 is studied. In 1 the trans-diastereose

Full text of DOI:10.1016/j.tetasy.2004.07.034

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