Enzymatic formation of an unnatural novel tetracyclic sesterterpene by β-amyrin synthase

Article abstract of DOI:10.1016/j.tetlet.2004.09.075

A C₂₅ oxidopolyprene was enzymatically converted to a novel unnatural tetracyclic sesterterpene by recombinant β-amyrin synthase from Pisum sativum, while a C₃₅ analogue did not afford any cyclization product. A convergent synthesis