Journal of Organic Chemistry p. 674 - 680 (1982)
Update date:2022-09-26
Topics:
Morrison, Robert W.
Styles, Virgil L.
New syntheses of pyrimido<4,5-c>pyridazines from 6-hydrazinoisocytosines and vicinal carbonyl reagents and reduction studies with selected members of this compound series are reported.Structural features required for pyrimidopyridazine formation from reactions of 2-amino-4-hydrazinopyrimidines with vicinal difunctional reagents and selectivity with respect to product substituent orientations are summarized.
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