Journal of Organic Chemistry p. 798 - 803 (1982)
Update date:2022-08-03
Topics:
Thies, Richard W.
Pierce, John R.
A synthetic methodology is described wherein a sequence of three ring expansions is used to convert cycloheptanone to 4'-methoxy-5,6-benzocyclodecenone, which was tested for estrogenic properties but showed no uterotrophic activity.Attempts to selectively expand the large ring by one more carbon to 8,9:13,14-diseco-18-norestrone were not successful.
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(2007)Doi:10.1021/ic00134a018
(1982)
