A short and Efficient Synthesis of (+/-)-Modhephene by a Stereoelectronically-Controlled Ene-Reaction

Article abstract of DOI:10.1002/hlca.19810640756

(+/-)-Modhephene (6) has been synthesized from the easily available trimethyl-pentalenone 1 in 6 steps in 26percent overall yield (Scheme 2).The remarkably smooth 1,4-addition/enolate trapping 1->2 and subsequent selenoxide elimination after oxidation fur