Structure-activity relationships of novel anti-malarial agents. Part 6: N-(4-arylpropionylamino-3-benzoylphenyl)-[5-(4-nitrophenyl)-2-furyl]acrylic acid amides

DOI: 10.1016/S0960-894X(03)00179-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1539 - 1541 (2003)

Update date:2022-08-02

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Authors:

Wiesner, Jochen

Fucik, Katharina

Kettler, Katja

Sakowski, Jacek

Ortmann, Regina

Jomaa, Hassan

Schlitzer, Martin

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Article abstract of DOI:10.1016/S0960-894X(03)00179-3

We have demonstrated that the p-trifluoromethylphenylpropionylamino residue at the 2-position of the core structure leads to an active benzophenone-type anti-malarial agent. The attempt to improve water solubility by introduction of an amino group into th

Full text of DOI:10.1016/S0960-894X(03)00179-3

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