Synthesis of (-)-(5R,6S)-5,6-epoxy-5,6-dihydro-β-ionone

Article abstract of DOI:10.1002/hlca.19810640827

Optically active 5,6-epoxy-5,6-dihydro-β-ionones have been prepared for the first time and their absolute configurations were determined by correlation with (-)-(S)-α-ionone.Acid catalyzed hydrolysis of the epoxide proceeds with retention of the configuration at C(6) and with inversion at C(5).