Tetrahedron Letters p. 4611 - 4614 (1981)
Update date:2022-09-26
Topics:
Chamberlin, A. Richard
Dezube, Milana
Dussault, Patrick
A stereoselective method for preparing 3-hydroxy-4-alkyl-γ-lactones is reported.Iodolactonization of 3-hydroxy-4-alkenoic acids produces predominantly the thermodynamically less stable 3,4-cis products, which undergo methanolysis to threo-epoxyalcohols.
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Doi:10.1021/jo00141a015
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(1982)
