Renin Inhibitors. Substitution of the Leucyl Residues of Leu-Leu-Val-Phe-OCH3 with 3-Amino-2-hydroxy-5-methylhexanoic Acid

DOI: 10.1021/jm00347a024

Source and publish data:

Journal of Medicinal Chemistry p. 605 - 610 (1982)

Update date:2022-08-03

Topics:: Authors:

Johnson, Rodney L.

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Article abstract of DOI:10.1021/jm00347a024

The 2S,3S and 2R,3S diastereoisomers of the hydroxy amino acid 3-amino-2-hydroxy-5-methylhexanoic acid (AHMHA) were synthesized and substituted for the leucyl residues of Leu-Leu-Val-Phe-OCH3 to yield the following analogues: AHMHA-Leu-Val-Phe-OCH3, AHMHA

Full text of DOI:10.1021/jm00347a024

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Article Doi

Renin Inhibitors. Substitution of the Leucyl Residues of Leu-Leu-Val-Phe-OCH3 with 3-Amino-2-hydroxy-5-methylhexanoic Acid

DOI: 10.1021/jm00347a024

Source and publish data:

Authors:

Article abstract of DOI:10.1021/jm00347a024

Full text of DOI:10.1021/jm00347a024

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