Total synthesis of racemic 2-desoxystemodinone and stemodinol; the identity of natural "stemodinol" with stemarin

Article abstract of DOI:10.1139/v82-099

Total synthesis of the naturally occuring diterpinoid 2-desoxystemodinone (3) and the diterpenoid structure 2 ("stemodinol") are described.The synthetic diterpenoid 2 was not identical to an authentic sample of "stemodinol".The authentic sample was found to be stemarin to which structure 2 had been erroneously assigned in the literature.It would appear that the diterpenoid represented by 2 has not been isolated from natural sources.