Deuterium-induced 13C NMR Nuclear Magnetic Resonance Isotope Shifts and 13C-2H Couplings for Signal Assignments and Determination of Deuteration Site in Cyclooctanone

Article abstract of DOI:10.1002/mrc.1270170415

Unambiguous signal assignments in the 13C spectra of monosubstituted cyclooctanones derived from the lead tetraacetate or silver oxide/bromine oxidations of the corresponding 1-monodeutero-alcohols have been obtained from deuterium-induced 13C isotope shifts and geminal and vicinal 13C-2H spin-spin coupling constants.The label in the ketones is shown to be in position 5.