α-Adrenergic Agents. 2. Synthesis and α1-Agonist Activity of 2-Aminotetralins

DOI: 10.1021/jm00344a009

Source and publish data:

Journal of Medicinal Chemistry p. 136 - 141 (1982)

Update date:2022-08-05

Topics:

Authors:

DeMarinis, R. M.

Shah, D. H.

Hall, R. F.

Hieble, J. P.

Pendleton, R. G.

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Article abstract of DOI:10.1021/jm00344a009

Substituted 2-aminotetralins are potent, selective, direct-acting agonists as postjunctional α₁ receptors.Within this series, substituent alterations on the ring, as well as on the nitrogen, change the potency of compounds by over three orders

Full text of DOI:10.1021/jm00344a009

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