Synthesis and biological evaluation of pyrido[2,3-b]pyrazine and pyrido[2,3-b]pyrazine-N-oxide as selective glycine antagonists

DOI: 10.1016/S0960-894X(96)00492-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2749 - 2754 (1996)

Update date:2022-08-04

Topics:

Authors:

Cugola, Alfredo

Donati, Daniele

Guarneri

Micheli, Fabrizio

Missio, Andrea

Pecunioso, Angelo

Reggiani, Angelo

Tarzia Tarzia

Zanirato

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(96)00492-1

Pyrido[2,3-b]pyrazines and pyrido[2,3-b]pyrazines-N-oxides have been synthesized and evaluated for in vitro/in vivo antagonistic activity at the glycine site on the NMDA receptor.

Full text of DOI:10.1016/S0960-894X(96)00492-1

Products guided by the article

Product name:5-Chloro-4,6-diMethylpyridine-2,3-diaMine

Cas No:827587-17-7

R&D Labs maybe for 827587-17-7

Henan Harvest Chem Co., Ltd

Contact:+86-371-86058576

Address:NO.32, Jingsan Road, Zhengzhou, China
Kaiping Genuine Biochemical Pharmaceutical Co.,Ltd.

Contact:+86-750-2881198

Address:No.1, Xinke Road, Shatang Town, Kaiping, Guangdong Province, P.R.China
SunaTech Inc.

Contact:+86 512 6287 2180

Address:398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu, P. R. China
Wuhan Kemi-Works Chemical Co., Ltd

website:http://www.kemiworks.com

Contact:86-27-85736489

Address:Rm. 1503, No. 164, Jianghan North Rd., Wuhan, 430022 China
Yancheng Creator Chemical Co., Ltd

Contact:0086-515-88710008 88710068 88710858 88710868

Address:No.21 Renming Road, Longgang Town, Yandu County,Yancheng City

Relevant to this article

Identification of new triarylethylene oxyalkanoic acid analogues as bone selective estrogen mimetics

Doi:10.1016/S0968-0896(01)00038-4
(2001)
Carbon dots as photocatalysts for organic synthesis: Metal-free methylene-oxygen-bond photocleavage

Doi:10.1039/c9gc03811f
(2020)
Zirconium sandwich complexes with η⁹ indenyl ligands: Well-defined precursors for zirconocene-mediated coupling reactions

Doi:10.1021/ja045072v
(2004)
Doi:10.1021/ja00387a043
(1982)
Doi:10.1007/BF00920268
()
SYNTHESIS OF A TRIFURCATED TETRASACCHARIDE USING DEHYDRATIVE GLYCOSYLATION

Doi:10.1246/cl.1982.1183
(1982)

Article Doi