Stereoselective Addition Reaction of Organolithium Reagents to Chiral Imines Derived from erythro-2-Amino-1,2-diphenylethanol

Article abstract of DOI:10.1246/cl.1995.235

The chiral imines prepared from an artificial chiral auxiliary, erythro-2-amino-1,2-diphenylethanol, and various aldehydes, reacted with organolithium reagents to give the corresponding chiral amines with excellent diastereofacial selectivity.