Chemistry of Heterocyclic Compounds p. 818 - 823 (1982)
Update date:2022-08-03
Topics:
Chekavichus, B. S.
Sausins, A. S.
Dubur, G. Ya.
The reactivity of the ester group of 3,5-dialkoxycarbonyl-1,4-dihydropyridines upon reaction with nucleophilic reagents increases when substituents are absent in the ortho positions relative to the ester group and also in the case of steric disruption of the coplanarity of the β-aminovinylcarbonyl system when substituents are introduced at the nitrogen atom in 2,6-dimethyl derivatives.Mono- and dicarboxylic acids were obtained by hydrolysis of such esters.Thus use of esters of propiolic acid esters and arylamines in the Hantzsch synthesis made it possible to obtain 1-aryl-2,6-unsubstituted derivatives of 1,4-dihydropyridine.
View MoreANHUI CHEM-BRIGHT BIOENGINEERING CO.,LTD
Contact:86-561-4080321
Address:No.8 Lieshan Industrial Zone of Huaibei
Contact:+86-519-86339586，13584329896
Address:Changzhou Scientific and Education Park
shanghai Tauto Biotech Co., Ltd
website:http://www.tautobiotech.com/en/index.htm
Contact:+86-21-51320588 ext. 8025
Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
Ningbo Inno Pharmchem Co., Ltd.
Contact:86-574-87319282
Address:6F-5,NO.163 RUIQING RD.,NINGBO 315000 CHINA
Suzhou Kangrun Pharmaceutical, Inc
Contact:86-512-63912376，63913329
Address:Building 2, No. 2358 ,Chang'an Rd, Wujiang Economic Development Zone Pioneering park, china
Doi:10.1039/c39820000858
(1982)Doi:10.1139/v82-403
(1982)Doi:10.1021/ja00341a041
(1983)Doi:10.1016/S0960-894X(02)00985-X
(2003)Doi:10.1021/ja01069a052
(1964)Doi:10.1016/S0960-894X(03)00306-8
(2003)
