PHOSPHORUS PENTOXIDE IN ORGANIC SYNTHESIS-I. PHOSPHORUS PENTOXIDE-AMINE HYDROCHLORIDE MIXTURES AS REAGENTS IN A NEW SYNTHESIS OF HYPOXANTHINES

DOI: 10.1016/0040-4020(82)80226-3

Source and publish data:

Tetrahedron p. 1435 - 1442 (1982)

Update date:2022-07-30

Topics: Reagents Organic synthesis Phosphorus pentoxide

Authors:

Nielsen, F. E.

Pedersen, E. B.

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Article abstract of DOI:10.1016/0040-4020(82)80226-3

A series of 23 new 1,7-dihydro-6H-purin-6-ones, 3a-3w have been prepared by heating ethyl 4-acylamino-1H-imidazole-5-carboxylates, 2a-2f and 2h, with primary amine hydrochlorides and phosphorus pentoxide in N,N-dimethylcyclohexylamine.Imidazo<4,5-d><1,3>o

Full text of DOI:10.1016/0040-4020(82)80226-3

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