Journal of Organic Chemistry p. 5177 - 5180 (1982)
Update date:2022-08-04
Topics:
Houlihan, William J.
Parrino, Vincent A.
2-Phenyl- and 2-(o-methylphenyl)imidazoline have been converted into their ortho- and α-lithiated species, respectively, by treatment with n-BuLi-hexane in THF.Treatment of these reagents with a variety of nucleophiles gave ortho- and α-substituted products.
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