Journal of Medicinal Chemistry p. 135 - 140 (1983)
Update date:2022-08-05
Topics:
Nair, M. G.
Otis, Eldridge B.
Kisliuk, Roy L.
Gaumont, Y.
The synthesis of 1',2',3',4',5',6'-hexahydrohomofolic acid (3), a close analogue of homofolic acid (2), has been carried out by replacement of the benzene ring of 2 with a cyclohexane ring.The synthetic methods employed here were based on the Boon-Leigh s
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