Nucleosides. 123. Synthesis of Antiviral Nucleosides: 5-Substituted 1-(2-Deoxy-2-halogeno-β-D-arabinofuranosyl)cytosines and -uracils. Some Structure-Activity Relationships

DOI: 10.1021/jm00356a007

Source and publish data:

Journal of Medicinal Chemistry p. 152 - 156 (1983)

Update date:2022-08-03

Topics:

Authors:

Watanabe, Kyoichi A.

Su, Tsann-Long

Klein, Robert S.

Chu, Chung K.

Matsuda, Akira

et al. et al.

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Article abstract of DOI:10.1021/jm00356a007

The syntheses of several 2'-halogeno-5-substituted-arabinofuranosylcytosines and -uracils are described, and relationships of structure to anti herpes virus activity in vitro were examined.Those arabinonucleosides containing the 2'-fluoro function exhibit

Full text of DOI:10.1021/jm00356a007

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