Synthetic carbapenem antibiotics III. 1-Methyl thienamycin

DOI: 10.1016/S0040-4039(00)89154-6

Source and publish data:

Tetrahedron Letters p. 587 - 590 (1985)

Update date:2022-08-02

Topics:

Authors:

Shih Shih

Cama Cama

Christensen

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Article abstract of DOI:10.1016/S0040-4039(00)89154-6

Total syntheses of 1α- and 1β-methyl thienamycin are reported. 1β-Methyl thienamycin retains the antibacterial activity of thienamycin and is highly resistant to hydrolysis by HPD-1 enzyme.

Full text of DOI:10.1016/S0040-4039(00)89154-6

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