The enantiospecific total synthesis of norsuaveoline

DOI: 10.1016/S0040-4039(98)01788-2

Source and publish data:

Tetrahedron Letters p. 8009 - 8012 (1998)

Update date:2022-07-30

Topics:

Authors:

Wang, Tao

Yu, Peng

Li, Jin Li, Jin

Cook, James M.

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Article abstract of DOI:10.1016/S0040-4039(98)01788-2

Norsuaveoline la has been synthesized enantiospecifically in 28% overall yield from commercially available D-(+)-tryptophan methyl ester via the asymmetric Pictet-Spengler reaction and a stereocontrolled oxy-anion Cope rearrangement as key steps.

Full text of DOI:10.1016/S0040-4039(98)01788-2

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Product name:D-(+)-N_bbenzyltryptophan methyl ester

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