General approach for the synthesis of macroline/sarpagine related indole alkaloids via the asymmetric Pictet-Spengler reaction: The enantiospecific synthesis of the N(a)-H, azabicyclo[3.3.1]nonone template

DOI: 10.1016/S0040-4039(97)01603-1

Source and publish data:

Tetrahedron Letters p. 6819 - 6822 (1997)

Update date:2022-07-29

Topics:

Authors:

Yu, Peng

Wang, Tao

Yu, Fuxiang

Cook, James M.

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Article abstract of DOI:10.1016/S0040-4039(97)01603-1

N(a)-H, N(b)-benzyltetracyclic ketone 1a, a potential intermediate for the synthesis of numerous sarpagine-related alkaloids, has been synthesized enantiospecifically from D-(+)-tryptophan via the asymmetric Pictet-Spengler reaction.

Full text of DOI:10.1016/S0040-4039(97)01603-1

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