SYNTHETIC APPROACH TOWARD MITOMYCINS. EFFICIENT SYNTHESIS OF MITOSANE PRECURSORS FROM (2,4-PENTADIENYL)-p-QUINONES

Article abstract of DOI:10.1246/cl.1982.1859

Introduction of 2,4-pentadienyl side chain to halogenated p-quinones is performed with (2,4-pentadienyl)trimethylstannane to afford 2-halo-3-(2,4-pentadienyl)-1,4-quinones.Pyrolytic decomposition of the corresponding azidoquinones derived from the obtaine