THE CHEMICAL SYNTHESIS OF THE Rp AND Sp DIASTEREOMERS OF THYMIDYL-(3'-5')THYMIDYL O,O-PHOSPHOROTHIOATE

DOI: 10.1016/S0040-4039(00)88727-4

Source and publish data:

Tetrahedron Letters p. 4289 - 4292 (1982)

Update date:2022-08-03

Topics:

Authors:

Uznanski, Bogdan

Niewiarowski, Wojciech

Stec, Wojciech J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)88727-4

The synthesis and separation of diastereomers of protected thymidyl-(3'-5')thymidyl O,O-phosphoranilidate (4) allowed to obtain in the stereospecific manner title compounds 5, whose absulute configuration at P atom was assigned enzymatically.T_P(S)T diastereomers (5) were obtained independently via "phosphite" procedure.

Full text of DOI:10.1016/S0040-4039(00)88727-4

Products guided by the article

Product name:5'-monomethoxytritylthymidyl(3'-5')-3'-monomethoxytritylthymidyl O-methyl phosphate

Cas No:84718-98-9

R&D Labs maybe for 84718-98-9

Changsha Yonta Industry Co., Ltd.

Contact:+ 86-731-8535 2228

Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
Shanghai Forever Biotech Co., Ltd.

Contact:+86-21-69734790

Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.
Jiangsu Chiatai Qingjiang Pharmaceutical Co.,Ltd

Contact:+86-517-86283327

Address:9 North Hantai Road, Huaian, China
Taizhou YOJOY Chemical Co., Ltd.

Contact:13857143241

Address:Yangfu Industrial Park, Xianju, Zhejiang, P. R. China
Beyond Pharmaceutical Co., Ltd

Contact:+86-571-8195-3185

Address:No. 13-1, Liansheng Road, Yuhang District

Relevant to this article

Reaction of 1-(o-aminophenyl)-1,2,3-triazole-5-thiols with cyclizing reagents

Doi:10.1023/B:RUJO.0000044551.48113.be
(2004)
Catalytic asymmetric synthesis of a potent thiomarinol antibiotic

Doi:10.1021/ja042827p
(2005)
Separated versus contact ion-pair structures in solution from their crystalline states: Dynamic effects on dinitrobenzenide as a mixed-valence anion

Doi:10.1021/ja043998x
(2005)
6′-Methylpyrido[3,4-b]norhomotropane: Synthesis and outstanding potency in relation to the α4β2 nicotinic receptor pharmacophore model

Doi:10.1016/j.bmcl.2004.12.069
(2005)
Novel multivalent mannose compounds and their inhibition of the adhesion of type 1 fimbriated uropathogenic E. coli

Doi:10.1016/j.tetasy.2004.11.014
(2005)
A practical procedure for the synthesis of 3-((E)-5-(2,3,4,5-tetramethoxy- 6-methylphenyl)-3-methylpent-3-enyl)-2,2-dimethyloxirane

Doi:10.1080/00304940409356633
(2004)

Article Doi